Department of Mathematics

Applied Mathematics

  •  Yufeng Liu, University of North Carolina at Chapel Hill
  •  ZOOM TALK (password the smallest prime > 100) - Learning Individualized Treatment Rules with Many Treatments
  •  02/23/2023
  •  2:30 PM - 3:30 PM
  •  C304 Wells Hall (Virtual Meeting Link)
  •  Mark A Iwen ()

Learning an optimal Individualized Treatment Rule (ITR) is a very important problem in precision medicine. In this talk, we consider the challenge when the number of treatment arms is large, and some groups of treatments in the large treatment space may work similarly for the patients. Motivated by the recent development of supervised clustering, we propose a novel adaptive fusion-based method to cluster the treatments with similar treatment effects together and estimate the optimal ITR simultaneously through a single convex optimization. We establish the theoretical guarantee of recovering the underlying true clustering structure of the treatments for our method. Finally, the superior performance of our method will be demonstrated via both simulations and a real data application on cancer treatment. This is joint work with Haixu Ma and Donglin Zeng at UNC-Chapel Hill.



Department of Mathematics
Michigan State University
619 Red Cedar Road
C212 Wells Hall
East Lansing, MI 48824

Phone: (517) 353-0844
Fax: (517) 432-1562

College of Natural Science