Department of Mathematics


  •  Spatial and stochastic dynamics in development and regeneration
  •  02/09/2017
  •  4:10 PM - 5:00 PM
  •  C304 Wells Hall
  •  Qing Nie, UC Irvine

In developing and renewing tissues, the properties of cells are controlled by secreted molecules from cells, their actions to the downstream regulators and genes, and transitions among different types of cells. The multiscale and stochastic nature of such spatial and dynamic systems presents tremendous challenges in synthesizing experimental observations and their understanding. In this talk, I will present several mathematical modeling frameworks with different complexity for systems ranging from single cells to multistage cell lineages. Questions of our interests include roles of feedbacks in regeneration speed, stem cell niche for tissue spatial organization, and crosstalk between epigenetic and genetic regulations. In addition to comparing our modeling outputs with experimental data, we will emphasize development of various mathematical and computational tools critical to success of using models in analyzing complex biological systems.



Department of Mathematics
Michigan State University
619 Red Cedar Road
C212 Wells Hall
East Lansing, MI 48824

Phone: (517) 353-0844
Fax: (517) 432-1562

College of Natural Science